3,923 research outputs found
Biomarkers in emergency medicine
Researchers navigate the ocean of biomarkers searching for proper targets and optimal utilization of them. Emergency medicine builds up the front line to maximize the utility of clinically validated biomarkers and is the cutting edge field to test the applicability of promising biomarkers emerging from thorough translational researches. The role of biomarkers in clinical decision making would be of greater significance for identification, risk stratification, monitoring, and prognostication of the patients in the critical- and acute-care settings. No doubt basic research to explore novel biomarkers in relation to the pathogenesis
is as important as its clinical counterpart. This special issue includes five selected research papers that cover a variety of biomarker- and disease-related topics
Influence of strain and oxygen vacancies on the magnetoelectric properties of multiferroic bismuth ferrite
The dependencies on strain and oxygen vacancies of the ferroelectric
polarization and the weak ferromagnetic magnetization in the multiferroic
material bismuth ferrite, BiFeO_3, are investigated using first principles
density functional theory calculations. The electric polarization is found to
be rather independent of strain, in striking contrast to most conventional
perovskite ferroelectrics. It is also not significantly affected by oxygen
vacancies, or by the combined presence of strain and oxygen vacancies. The
magnetization is also unaffected by strain, however the incorporation of oxygen
vacancies can alter the magnetization slightly, and also leads to the formation
of Fe^{2+}. These results are discussed in light of recent experiments on
epitaxial films of BiFeO_3 which reported a strong thickness dependence of both
magnetization and polarization.Comment: 9 pages, 3 figure
Molecular cytogenetic mapping of Cucumis sativus and C. melo using highly repetitive DNA sequences
Chromosomes often serve as one of the most important molecular aspects of studying the evolution of species. Indeed, most of the crucial mutations that led to differentiation of species during the evolution have occurred at the chromosomal level. Furthermore, the analysis of pachytene chromosomes appears to be an invaluable tool for the study of evolution due to its effectiveness in chromosome identification and precise physical gene mapping. By applying fluorescence in situ hybridization of 45S rDNA and CsCent1 probes to cucumber pachytene chromosomes, here, we demonstrate that cucumber chromosomes 1 and 2 may have evolved from fusions of ancestral karyotype with chromosome number n= 12. This conclusion is further supported by the centromeric sequence similarity between cucumber and melon, which suggests that these sequences evolved from a common ancestor. It may be after or during speciation that these sequences were specifically amplified, after which they diverged and specific sequence variants were homogenized. Additionally, a structural change on the centromeric region of cucumber chromosome 4 was revealed by fiber-FISH using the mitochondrial-related repetitive sequences, BAC-E38 and CsCent1. These showed the former sequences being integrated into the latter in multiple regions. The data presented here are useful resources for comparative genomics and cytogenetics of Cucumis and, in particular, the ongoing genome sequencing project of cucumbe
Magnetic exchange interaction between rare-earth and Mn ions in multiferroic hexagonal manganites
We report a study of magnetic dynamics in multiferroic hexagonal manganite
HoMnO3 by far-infrared spectroscopy. Low-temperature magnetic excitation
spectrum of HoMnO3 consists of magnetic-dipole transitions of Ho ions within
the crystal-field split J=8 manifold and of the triangular antiferromagnetic
resonance of Mn ions. We determine the effective spin Hamiltonian for the Ho
ion ground state. The magnetic-field splitting of the Mn antiferromagnetic
resonance allows us to measure the magnetic exchange coupling between the
rare-earth and Mn ions.Comment: accepted for publication in Physical Review Letter
Time-reversal symmetry breaking in circuit-QED based photon lattices
Breaking time-reversal symmetry is a prerequisite for accessing certain
interesting many-body states such as fractional quantum Hall states. For
polaritons, charge neutrality prevents magnetic fields from providing a direct
symmetry breaking mechanism and similar to the situation in ultracold atomic
gases, an effective magnetic field has to be synthesized. We show that in the
circuit QED architecture, this can be achieved by inserting simple
superconducting circuits into the resonator junctions. In the presence of such
coupling elements, constant parallel magnetic and electric fields suffice to
break time-reversal symmetry. We support these theoretical predictions with
numerical simulations for realistic sample parameters, specify general
conditions under which time-reversal is broken, and discuss the application to
chiral Fock state transfer, an on-chip circulator, and tunable band structure
for the Kagome lattice.Comment: minor revisions, version published in PRA; 19 pages, 13 figures, 2
table
Quasi-particle scattering and protected nature of topological states in a parent topological insulator BiSe
We report on angle resolved photoemission spectroscopic studies on a parent
topological insulator (TI), BiSe. The line width of the spectral
function (inverse of the quasi-particle lifetime) of the topological metallic
(TM) states shows an anomalous behavior. This behavior can be reasonably
accounted for by assuming decay of the quasi-particles predominantly into bulk
electronic states through electron-electron interaction and defect scattering.
Studies on aged surfaces reveal that topological metallic states are very much
unaffected by the potentials created by adsorbed atoms or molecules on the
surface, indicating that topological states could be indeed protected against
weak perturbations.Comment: accepted for publication in Phys. Rev. B(R
Zeeman smearing of the Coulomb blockade
Charge fluctuations of a large quantum dot coupled to a two-dimensional lead
via a single-mode good Quantum Point Contact (QPC) and capacitively coupled to
a back-gate, are investigated in the presence of a parallel magnetic field. The
Zeeman term induces an asymmetry between transmission probabilities for the
spin-up and spin-down channels at the QPC, producing noticeable effects on the
quantization of the grain charge already at low magnetic fields. Performing a
quantitative analysis, I show that the capacitance between the gate and the
lead exhibits - instead of a logarithmic singularity - a reduced peak as a
function of gate voltage. Experimental applicability is discussed.Comment: 5 pages, 3 figures (Final version
Plasma density measurements using chirped pulse broad-band Raman amplification
Stimulated Raman backscattering is used as a non-destructive method to determine the density of plasma media at localized positions in space and time. By colliding two counter-propagating, ultra-short laser pulses with a spectral bandwidth larger than twice the plasma frequency, amplification occurs at the Stokes wavelengths, which results in regions of gain and loss separated by twice the plasma frequency, from which the plasma density can be deduced. By varying the relative delay between the laser pulses, and therefore the position and timing of the interaction, the spatio-temporal distribution of the plasma density can be mapped out
- …